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1

Molecular Targeting of Cell Death Signal Transduction Pathways in Cancer

Petak, Istvan, Houghton, Janet, Kopper, Laszlo

Journal:

Current Signal Transduction Therapy

Year:

2006

Language:

english

File:

PDF, 374 KB

english, 2006

2

Natural Warning Signs of Tsunamis: Human Sensory Experience and Response to the 2004 Great Sumatra Earthquake and Tsunami in Thailand

Gregg, Chris E., Houghton, Bruce F., Paton, Douglas, Lachman, Roy, Lachman, Janet, Johnston, David M., Wongbusarakum, Supin

Journal:

Earthquake Spectra

Year:

2006

Language:

english

File:

PDF, 201 KB

english, 2006

3

On the mechanism of cytotoxicity of fluorinated pyrimidines in four human colon adenocarcinoma xenografts maintained in immune-deprived mice

Janet A. Houghton, Peter J. Houghton

Journal:

Year:

1980

Language:

english

File:

PDF, 732 KB

english, 1980

4

Phase II study of 5-fluorouracil/leucovorin for pediatric patients with malignant solid tumors

Charles B. Pratt, William H. Meyer, Nanna Howlett, Edwin C. Douglass, Laura C. Bowman, Debbie Poe, Kevin Mounce, Larry E. Kun, Janet A. Houghton

Journal:

Year:

1994

Language:

english

File:

PDF, 512 KB

english, 1994

5

ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum

Qian Wang, Lynda Elghazi, Sophie Martin, Isabelle Martins, R. Satish Srinivasan, Xin Geng, Mark Sleeman, Patrick Collombat, Janet Houghton, Beatriz Sosa-Pineda

Journal:

Developmental Dynamics

Year:

2008

Language:

english

File:

PDF, 1.76 MB

english, 2008

6

Development of resistance to vincristine in a childhood rhabdomyosarcoma growing in immune-deprived mice

Janet A. Houghton, Peter J. Houghton, Garrett M. Brodeur, Alexander A. Green

Journal:

International Journal of Cancer

Year:

1981

Language:

english

File:

PDF, 677 KB

english, 1981

7

Influence of guanine nucleotides on vincristine binding in tumor cytosols and purified tubulin: Evidence for an inhibitor of vincristine binding

Laura C. Bowman, Janet A. Houghton, Peter J. Houghton

Journal:

Journal of Cellular Physiology

Year:

1990

Language:

english

File:

PDF, 754 KB

english, 1990

8

Chromatographic analysis of Vinca alkaloids in human neoplastic tissues and host (mouse) tissues after injection in vivo or after incubation in vitro

Janet A. Houghton, Pamela M. Torrance, Peter J. Houghton

Journal:

Analytical Biochemistry

Year:

1983

Language:

english

File:

PDF, 374 KB

english, 1983

9

Biochemical mechanisms in colon xenografts: Thymidylate synthase as a target for therapy

Peter J. Houghton, Janet A. Houghton, Bonni J. Hazelton, Saeed Radparvar

Journal:

Investigational New Drugs

Year:

1989

Language:

english

File:

PDF, 764 KB

english, 1989

10

Antitumor diarylsulfonylureas: novel agents with unfulfilled promise

Peter J. Houghton, Janet A. Houghton

Journal:

Investigational New Drugs

Year:

1996

Language:

english

File:

PDF, 818 KB

english, 1996

11

Evaluation of 3-(p-fluorophenyl)-l-alanyl-3-[m-bis(2-chloroethyl)aminophenyl]-l-alanyl-l-methionine ethyl ester HCl (PTT.119) against xenografts of human rhabdomyosarcoma

Peter J. Houghton, Ruby Tharp, Janet A. Houghton, J. F. Holland, J. George Bekesi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 456 KB

english, 1988

12

Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors

Peter J. Houghton, Pamela J. Cheshire, Leann Myers, Clinton F. Stewart, Timothy W. Synold, Janet A. Houghton

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.06 MB

english, 1992

13

Factors that influence the therapeutic activity of 5-fluorouracil [6RS]leucovorin combinations in colon adenocarcinoma xenografts

Janet A. Houghton, Larry G. Williams, Susan K. Loftin, Pamela J. Cheshire, Christopher L. Morton, Peter J. Houghton, Alain Dayan, Jacques Jolivet

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.24 MB

english, 1992

14

Evaluation of N-(5-indanylsulfonyl)-N′-(4-chlorophenyl)-urea against xenografts of pediatric rhabdomyosarcoma

Peter J. Houghton, Janet A. Houghton, Leann Myers, Pamela Cheshire, J. Jeffry Howbert, Gerald B. Grindey

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 498 KB

english, 1989

15

Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of smac/DIABLO from the mitochondria

Katalin Nagy, Kinga Székely-Szüts, Kamel Izeradjene, Leslie Douglas, Mike Tillman, Helga Barti-Juhász, Massimo Dominici, Carlotta Spano, Gian Luca Cervo, Pierfranco Conte, Janet A Houghton, Rudolf Mih

Journal:

Pathology & Oncology Research

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

16

Shared pathways: Death receptors and cytotoxic drugs in cancer therapy

Istvan Petak, Janet A. Houghton

Journal:

Pathology & Oncology Research

Year:

2001

Language:

english

File:

PDF, 1.28 MB

english, 2001

17

Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against pediatric and adult central nervous system tumor xenografts

C. Bradley Hare, Gertrude B. Elion, Peter J. Houghton, Janet A. Houghton, Stephen Keir, Susan L. Marcelli, Darell D. Bigner, H. S. Friedman

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 127 KB

english, 1996

18

The impact of the 2004 tsunami on coastal Thai communities: assessing adaptive capacity

Douglas Paton, Chris E. Gregg, Bruce F. Houghton, Roy Lachman, Janet Lachman, David M. Johnston, Supin Wongbusarakum

Journal:

Year:

2008

Language:

english

File:

PDF, 222 KB

english, 2008

19

Training: Undergraduate public health education: a workforce perspective

Susan Houghton, Annette Braunack-Mayer, Janet E. Hiller

Journal:

Australian and New Zealand Journal of Public Health

Year:

2002

Language:

english

File:

PDF, 43 KB

english, 2002

20

Expression of genes that regulate Fas signalling and Fas-mediated apoptosis in colon carcinoma cells

Tillman, David M, Harwood, Franklin G, Gibson, Alice A, Houghton, Janet A

Journal:

Cell Death & Differentiation

Year:

1998

Language:

english

File:

PDF, 331 KB

english, 1998

21

Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines

Izeradjene, Kamel, Douglas, Leslie, Delaney, Addison, Houghton, Janet A

Journal:

Year:

2005

Language:

english

File:

PDF, 351 KB

english, 2005

22

Serious adverse incidents with the usage of low molecular weight heparins in patients with chronic kidney disease

Vasim Farooq, Janet Hegarty, Thangavelu Chandrasekar, Elizabeth H. Lamerton, Sandip Mitra, John B. Houghton, Philip A. Kalra, Stephen Waldek, Donal J. O’Donoghue, Grahame N. Wood

Journal:

American Journal of Kidney Diseases

Year:

2004

Language:

english

File:

PDF, 122 KB

english, 2004

23

Corticosteroid related changes in body mass index in children and adolescents with rheumatic diseases

Shiff, Natalie, Brant, Rollin, Cabral, David A, Guzman, Jaime, Dent, Peter B, Ellsworth, Janet E, Houghton, Kristin M, Huber, Adam, Jurencak, Roman, Lang, Bianca A, Larche, Maggie, LeBlanc, Claire MA,

Journal:

Pediatric Rheumatology

Year:

2012

Language:

english

File:

PDF, 141 KB

english, 2012

24

Incident vertebral fractures 12 months following glucocorticoid initiation in children with rheumatic disorders

Lang, Bianca A, Rodd, Celia, Ramsay, Timothy, Cabral, David A, Dent, Peter B, Ellsworth, Janet E, Houghton, Kristin M, Huber, Adam, Jurencak, Roman, Larché, Maggie, LeBlanc, Claire MA, Lentle, Brian,

Journal:

Pediatric Rheumatology

Year:

2012

Language:

english

File:

PDF, 101 KB

english, 2012

25

Characteristics of thymidylate synthase purified from a human colon adenocarcinoma

Saeed Radparvar, Peter J. Houghton, Janet A. Houghton

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 839 KB

english, 1988

26

GTP influences the binding of vincristine in human tumor cytosols

Laura C. Bowman, Janet A. Houghton, Peter J. Houghton

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 348 KB

english, 1986

27

5-Fluorouracil in combination with hypoxanthine and allopurinol: Toxicity and metabolism in xenografts of human colonic carcinomas in mice

Janet A. Houghton, Peter J. Houghton

Journal:

Biochemical Pharmacology

Year:

1980

Language:

english

File:

PDF, 274 KB

english, 1980

28

Studies with 4'-deoxyepivincristine (vinepidine), a semisynthetic vinca alkaloid

Kimberly Mullin, Peter J. Houghton, Janet A. Houghton, Marc E. Horowitz

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 539 KB

english, 1985

29

Relationship between 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration, in xenografts of human colon adenocarcinomas

Janet A. Houghton, Karen D. Weiss, Larry G. Williams, Pamela M. Torrance, Peter J. Houghton

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 1.14 MB

english, 1986

30

Determination of thymidylate synthase activity in colon tumor tissues after treatment with 5-fluorouracil

Janet A. Houghton, Saeed Radparvar, Pamela M. Torrance, Larry G. Williams, Peter J. Houghton

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 561 KB

english, 1987

31

Relationship between binding affinity, retention and sensitivity of human rhabdomyosarcoma xenografts to vinca alkaloids

Janet A. Houghton, Larry G. Williams, Richard K. Dodge, Stephen L. George, Bonni J. Hazelton, Peter J. Houghton

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 968 KB

english, 1987

32

Relationships between tumor responsiveness, vincristine pharmacokinetics and arrest of mitosis in human tumor xenografts

Julie K. Horton, Peter J. Houghton, Janet A. Houghton

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 731 KB

english, 1988

33

Formation and stability of vincristine-tubulin complex in kidney cytosols: Role of GTP and GTP hydrolysis

Laura C. Bowman, Janet A. Houghton, Peter J. Houghton

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 659 KB

english, 1988

34

Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenografT

Saeed Radparvar, Peter J. Houghton, Janet A. Houghton

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 895 KB

english, 1989

35

Modulation by verapamil of vincristine pharmacokinetics and toxicity in mice bearing human tumor xenografts

Julie K. Horton, Kuntebommanahalli N. Thimmaiah, Janet A. Houghton, Marc E. Horowitz, peter J. Houghton

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 1.31 MB

english, 1989

36

Cellular pharmacology of 5-fluorouracil in a human colon adenocarcinoma cell line selected for thymidine kinase deficiency

Saeed Radparvar, Peter J. Houghton, Glen Germain, Janet Pennington, Atiqur Rahman, Janet A. Houghton

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 789 KB

english, 1990

37

Studies on the cellular pharmacology of N-(4-methylphenylsulfonyl)-N′-(4-chlorophenyl)-urea

Peter J. Houghton, Frank C. Bailey, Glen S. Germain, Gerald B. Grindey, J.Jeffry Howbert, Janet A. Houghton

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 828 KB

english, 1990

38

The Therapeutic Effect of Functional and Transcutaneous Electric Stimulation on Improving Gait Speed in Stroke Patients: A Meta-Analysis

Shawn M. Robbins, Pamela E. Houghton, M. Gail Woodbury, Janet L. Brown

Journal:

Archives of Physical Medicine and Rehabilitation

Year:

2006

Language:

english

File:

PDF, 150 KB

english, 2006

39

Schedule-dependent Efficacy of Camptothecins in Models of Human Cancer

PETER J. HOUGHTON, CLINTON F. STEWART, WILLIAM C. ZAMBONI, JOYCE THOMPSON, XIALOLONG LUO, MARY K. DANKS, JANET A. HOUGHTON

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 723 KB

english, 1996

40

Characterisation of platinum-based fuel cell catalyst materials using 195Pt wideline solid state NMR

Rees, Gregory J., Orr, Simon T., Barrett, Laurence O., Fisher, Janet M., Houghton, Jennifer, Spikes, Geoffrey H., Theobald, Brian R. C., Thompsett, David, Smith, Mark E., Hanna, John V.

Journal:

Physical Chemistry Chemical Physics

Year:

2013

Language:

english

File:

PDF, 2.25 MB

english, 2013

41

Erratum

Houghton, Janet A., Schmidt, Colleen, Houghton, Peter J.

Journal:

Precambrian Research

Year:

1989

File:

PDF, 15 KB

1989

42

The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenografts

Houghton, Janet A., Schmidt, Colleen, Houghton, Peter J.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1982

Language:

english

File:

PDF, 912 KB

english, 1982

43

Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma

Houghton, Janet A., Houghton, Peter J.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1983

Language:

english

File:

PDF, 977 KB

english, 1983

44

Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell line

Gündüz, Ufuk, Elliott, Mark S., Seubert, Patricia H., Houghton, Janet A., Houghton, Peter J., Trewyn, Ronald W., Katze, Jon R.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1992

Language:

english

File:

PDF, 882 KB

english, 1992

45

Childhood rhabdomyosarcoma xenografts: Responses to DNA-interacting agents and agents used in current clinical therapy

Houghton, Janet A., Cook, Ruby L., Lutz, Pamela J., Houghton, Peter J.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1984

Language:

english

File:

PDF, 634 KB

english, 1984

46

O6-alkylguanine-DNA Alkyltransferase Activity Correlates with the Therapeutic Response of Human Rhabdomyosarcoma Xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea

Thomas P. Brent, Peter J. Houghton and Janet A. Houghton

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 636 KB

english, 1985

47

Mutants of Human Colon Adenocarcinoma, Selected for Thymidylate Synthase Deficiency

Peter J. Houghton, Glen S. Germain, Bonnie J. Hazelton, Janet W. Pennington and Janet A. Houghton

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 971 KB

english, 1989

48

Thymineless Death in Colon Carcinoma Cells is Mediated via Fas Signaling

Janet A. Houghton, Franklin G. Harwood and David M. Tillman

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.32 MB

english, 1997

49

FOXO1a Acts as a Selective Tumor Suppressor in Alveolar Rhabdomyosarcoma

Philippe R. J. Bois, Kamel Izeradjene, Peter J. Houghton, John L. Cleveland, Janet A. Houghton and Gerard C. Grosveld

Journal:

The Journal of Cell Biology

Year:

2005

Language:

english

File:

PDF, 2.54 MB

english, 2005

50

Synthesis and chemical characterization of N-substituted phenoxazines directed toward reversing vinca alkaloid resistance in multidrug-resistant cancer cells

Thimmaiah, Kuntebommanahalli N., Horton, Julie K., Seshadri, Ramakrishnan, Israel, Mervyn, Houghton, Janet A., Harwood, Franklin C., Houghton, Peter J.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.02 MB

english, 1992

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